Hen Egg - white Lysozyme Crystals

نویسندگان

  • Haruhiko Koizumi
  • Masaru Tachibana
  • Kenichi Kojima
  • Irena Wolska
  • Dorota Maciejewska
چکیده

Proton tautomerism is a general phenomenon in organic molecules and plays a vital role in many fields of chemistry and biochemistry. The tautomerism of salicylideneanilines [eq(1)] has attracted a considerable attention because it is closely related to thermoand photochromism. Salicylideneanilines greatly favor the enol form over the cis-keto form in the gas phase. We demonstrate here that the instability of the cis-keto form is substantially reduced by intermolecular hydrogen bonding and also by self-association, on the basis of our variable temperature X-ray crystallographic and UV-vis absorption spectroscopic studies.[1]-[3].

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تاریخ انتشار 2005